Pakistan cricket has been known for producing amazing bowling talents over the years. Interestingly, there is no overseas bowler in the top 10 of this list. All the spots have been occupied by Pakistani bowlers, all of whom have played for the national team at some point in time.
Most Wickets in PSL
| Player | Matches | Wickets | BBI | Ave | Econ | 4WI | 5WI |
| Wahab Riaz | 55 | 76 | 3/17 | 18.71 | 7.01 | 0 | 0 |
| Hasan Ali | 45 | 59 | 4/15 | 20.93 | 7.47 | 3 | 0 |
| Mohammad Amir | 48 | 49 | 4/25 | 25.48 | 7.15 | 2 | 0 |
| Mohammad Nawaz | 52 | 49 | 4/13 | 25.55 | 7.12 | 1 | 0 |
| Sohail Tanvir | 46 | 48 | 4/13 | 25.14 | 7.55 | 2 | 0 |
| Faheem Ashraf | 31 | 46 | 6/19 | 18.52 | 8.12 | 1 | 1 |
| Mohammad Sami | 36 | 42 | 5/8 | 20.83 | 6.88 | 0 | 1 |
| Shahid Afridi | 46 | 42 | 5/7 | 23.61 | 6.76 | 0 | 1 |
| Sohail Khan | 34 | 37 | 3/23 | 27.37 | 8.57 | 0 | 0 |
| Shadab Khan | 41 | 37 | 3/13 | 28.18 | 7.16 | 0 | 0 |
